It will be the start of a new era for the hosts in Ewen McKenzie's first game as coach, and they will be hoping to catch their old rivals off guard in the first match of the Rugby Championship this year.
The All Blacks will be missing key players in the injured pair of Dan Carter and Liam Messam, whilst there will also be question marks over skipper Richie McCaw who recently returned from a six month break from the game.
McKenzie gets his chance after replacing Robbie Deans, who won only three of his 18 Tests against New Zealand and whose reign ended after the British and Irish Lions hammered the Wallabies 41-16 last month to take the three-match series.
He is promising a fresh coaching approach and has opted for uncapped Matt Toomua as his playmaker instead of Quade Cooper, with whom he formed a close coach-player relationship during his four years at the Reds.
"Never make assumptions," McKenzie said.
"When I was coaching Quade at the Reds I only had Quade at the Reds. None of this says Quade has done anything wrong. Quade is going quite well. In the end we drilled down to what we actually need and we favoured Matt over Quade.
"As we developed how we wanted to play, it became more and more obvious it was going to be a better way to start the game," he added.
If Toomua can spark the Wallabies' backline then the plan is for the exciting Israel Folau to get more of the action and put the All Blacks' defence under pressure.
Folau was devastating at times on the wing against the Lions, most notably in his sensational two-try Test debut in Brisbane, but the Wallabies admit they underutilised him in that series defeat.
"He's a guy you want to get the ball because he makes things happen," skipper James Horwill said. "He's got free rein to make sure he gets the ball as much as he wants.
"He understands that and he's a guy who makes defences worry."
The All Blacks beat the Wallabies in Sydney last year, but the last time to the two sides met the match ended in a 18-18 draw in Brisbane so they will be keen to assert their dominance.
